Student Presentations
(National and International Meetings)

Presentations 2017-2023

1. Randy Irizarry-Álvarez, Manuel Delgado-Vélez, Negin Martin, Jerrel L. Yakel, and José A. Lasalde-Dominicci, “Assessing the Cholinergic Anti-Inflammatory Response in Human Macrophages Exposed to the Spike Protein of the SARS-CoV-2 Strain from Wuhan, China” Annual Biomedical Research Conference for Minority Students (ABRCMS) Report, November 9-12, 2022.


2. Randy Irizarry-Álvarez, Manuel Delgado-Vélez, Negin Martin, Jerrel L. Yakel, and José A. Lasalde-Dominicci, “Assessing the Cholinergic Anti-Inflammatory Response in Human MacrophagesExposed to the Spike Protein of the SARS-CoV-2 Strain from Wuhan, China” 30th Puerto Rico Neuroscience Conference 2022 Report on December 3,2022


3. Adriana Rodríguez-Aponte, Rolando Irizarry-Álvarez, Bismark Madera, Negin Martin, Jerrel L. Yakel, Manuel Delgado-Vélez, & José A. Lasalde-Dominicci, “SARS CoV-2 Soluble Spike Alters Alpha-7 Nicotinic Acetylcholine Receptor (α7-nAChR) Levels in Human Neuronal Cells” 30th Puerto Rico Neuroscience Conference 2022 Report on December 3, 2022


4. Randy Irizarry-Álvarez, Manuel Delgado-Vélez, Negin Martin, Jerrel L. Yakel, and José A. Lasalde-Dominicci, “Assessing the Cholinergic Anti-Inflammatory Response in Human Macrophages Exposed to the Spike Protein of the SARS-CoV-2 Strain from Wuhan, China” National IDeA Symposium of Biomedical Research Excellence (INSBRE) Report on December 12,2022


5. Randy Irizarry-Álvarez, Manuel Delgado-Vélez, Negin Martin, Jerrel L. Yakel, and José A. Lasalde-Dominicci, “Assessing the Cholinergic Anti-Inflammatory Response in Human Macrophages Exposed to the Spike Protein of the SARS-CoV-2 Strain from Wuhan, China” 14th RISE Area Conference Report on April 1, 2023


6. Cunningham, CR., Dimopoulos, YP., Denai, DR., Delgado-Velez, M., Lasalde-Dominicci, JA., Woo, CC., Prieto, VG., Ballester, LY., Aung, PP. Expression of nicotinic acetylcholine receptor in Merkel Cell Carcinoma: its potential etiologic and prognostic role. United States and Canadian Academy of Pathology (USCAP) 2022 Annual Meeting, New Orleans, March 11-16, 2023.


7. Cunningham, CR., Dimopoulos, YP., Delgado-Velez, M., Lasalde-Dominicci, JA., Woo, CC., Prieto, VG., Ballester, LY., Aung, PP. Alpha-5 Nicotinic Acetylcholine Receptor Expression in Merkel Cell Carcinoma: Possible Etiologic Roles. United States and Canadian Academy of Pathology (USCAP) 112th Annual Meeting, New Orleans, March 11-16, 2023.


8. Del Toro Dominguez, JJ; Castro-Martínez, A.; Bauer, W.; Gonzalez-Vega, P., Rodriguez-Martínez, J. A., Lasalde-Dominicci, J. A. Subcloning of a 10x Histidine Tag in the Neuronal Nicotinic Receptor alpha4beta2 for Structural Studies. 7th Annual BioXFEL International Conference in San Juan, Puerto Rico, January 28-30, 2020.


9. Rodríguez-Cordero, J.A.; Quesada-González, Orestes; Lasalde-Dominicci, José A.; “High-Throughput Crystallographic Screening Method for Membrane Proteins at Membrane Potentials”. 7th Annual BioXFEL International Conference in San Juan, Puerto Rico, January 28-30, 2020.


10. Rodríguez-Cordero, J.A; Muñiz-Sarriera, Adrián; Quesada-González, Orestes; Lasalde-Dominicci, José A.; “High-Throughput Crystallographic Screening Method for Membrane Proteins at Resting Membrane Potential”. COBRE 6th Annual Retreat. Hotel El Convento, San Juan, Puerto Rico, May 13, 2019.


11. Poueymirou-La Torre, M. J., Aviles-Reymundi, G., Maldonado-Hernandez, R., Maysonet-Navarro, C., Quesada, O., Lasalde-Dominicci, J. Essential Role of CHS in Ion Channel Functioning and Thermal Stability of The Native Muscle-Type nAChR-Detergent-Complex. Louis Stokes Alliance for Minority Participation – Junior Technical Meeting 2019, Mayaguez, PR. May 4th, 2019.


12. Lasalde-Dominicci, José A. et al., “Role of R5-tropic gp120JRFL-mediated α7 nicotinic acetylcholine receptor upregulation in the cholinergic anti-inflammatory response” 64 Biophysical meeting San Diego California, February 15-19, 2020


13. Lasalde-Dominicci, José A., Pearl Akamine, José A. González-Feliciano, Coral Capó-Vélez1Manuel Delgado-Vélez, Abel Baerga-Ortiz “A Center for the Rapid Analysis of Clinical-grade Biologics: The Biophysical Characterization of HIV-1 Env Protein” Viruses 2020, Barcelona, February 2-6, 2020, Barcelona Spain.


14. Maldonado-Hernández, R., Gonzalez, J.A., Colon, J.O., Maysonet, C., Quesada, O. and Lasalde-Dominicci, J. Preparation and biophysical characterization of nAChR for high-resolution studies. Biophysical Society 63nd Annual Meeting, Baltimore, Maryland, Baltimore Convention Center March 2-6, 2019.


15. Maldonado-Hernández, R., Gonzalez, J.A., Colon, J.O., Maysonet, C., Quesada, O. and Lasalde-Dominicci, J. Optimization and characterization of nAChR for high-resolution studies. 6th BioXFEL Conference, San Diego CA, February 12-14, 2019.


16. Villalobos-Santos, JC., Lasalde-Dominicci, J., “Expression of the Human a4b2 nAChR by Recombinant Baculovirus Transduction and Ion-Channel Functional Characterization”, 6th BioXFEL Conference, San Diego CA, February 12-14, 2019.


17. Silva-Madera, C., Maldonado-Hernández, R., Colón, J., Quesada, O., Lasalde-Dominicci, J. Improved Preparation of nAChR-Detergent Complexes for Structural Studies. Forward Research & Innovation Summit 2018, San Juan, Puerto Rico, November 10, 2018.


18. Maldonado-Hernández, R., Maysonet, C., Pastrana A., Silva, C., Albino E., Quesada, O. and Lasalde-Dominicci, J. Essential Role of CHS in the Ion Channel function and Thermal Stability of Native Muscle-type nAChR-detergent-complex. Neuroscience 2018, SfN’s Annual Meeting, San Diego, California, November 3-7, 2018.


19. Muñiz Sarriera, A.B, Rodríguez-Cordero, J.A., Lasalde-Dominicci, J.A. Purification and Crystallization of Model Transmembranal Proteins. Junior Technical Meeting 2018, University of Turabo, Gurabo, P.R, April 28, 2018. (Oral Presentation)


20. Rodriguez-Tirado, C., Lasalde-Dominicci, J., Colón-Sáez, J.O. Modulation of nicotinic acetylcholine receptors by cannabinoids. 38TH Annual Research and Education Forum, San Juan, PR. April 20 2018.


21. Reilly-Andújar, F., Lasalde-Dominicci, J., Colón-Sáez, J.O. Characterization of the Effects of Novel Positive Allosteric Modulators on the Functionality of the α7 Nicotinic Acetylcholine Receptor (nAChR). Experimental Biology 2018 Meeting, San Diego, CA, April 21-25, 2018.


22. Rodriguez-Tirado, C., Lasalde-Dominicci, J.A., Colon-Saez, J.O. Modulation of nicotinic acetylcholine receptors by cannabinoids. Experimental Biology Meeting, San Diego, CA. April 21-25, 2018.


23. Maldonado-Hernández, R., Silva, C., Pastrana A., Maysonet, C., Quesada, O. and Lasalde-Dominicci, J.A. Improved Purification and Crystal Formation of Native Muscle-type nAChR Using mAbs. Biophysical Society 62nd Annual Meeting. Moscone Center, San Francisco, California, February 17-21, 2018.


24. Villalobos-Santos, J.C., Lasalde-Dominicci, J.A. “Expression and Characterization of the Human a 4 b 2 Nicotinic Acetylcholine Receptor for Functional Characterization Using Macroscopic Electrophysiology”, Biophysical Society Meeting, San Francisco CA, February 17-21 2018.


25. Valdés-Fernández B.N., Wei A., Lopez-Cruz L.M., Reilly-Andújar F., Cobo-Torres B., González-Martinez O.G., Cordero-Villamil R., and Lasalde-Dominicci J.A. Preparation of Nicotinic Acetylcholine Receptor Detergent Complexes for Structural Studies: Assessment of Purity, Functionality and Aggregation Analysis. 61th Annual Biophysical Society Meeting, New Orleans. February 11-15 2017.


26. Akamine P., González-Feliciano, J.A., Capó-Vélez, C., Meléndez, L.M., Delgado-Vélez, M., Lasalde-Dominicci, J.A., Baerga-Ortiz, A. A Center for the Rapid Analysis of Clinical-grade Biologics: The Biophysical Characterization of HIV-1 Env Protein as a Vaccine Candidate. Lilly Academy Technical Forum, San Juan, PR, March 24, 2017.


27. Akamine P., González-Feliciano, J.A., Capó-Vélez, C., Meléndez, L.M., Delgado-Vélez, M., Lasalde-Dominicci, J.A., Baerga-Ortiz, A. A Center for the Rapid Analysis of Clinical-grade Biologics: The Biophysical Characterization of HIV-1 Env Protein as a Vaccine Candidate. University of Puerto Rico – Medical Sciences Campus 37th Annual Research and Education Forum, San Juan, PR, April 19, 2017.


28. Cotto-Ríos S., Quiroz-Figueroa K., Hernández-Camacho P., Quesada O., Colón J. O., Lasalde-Dominicci J. A., Effects of HIV-1 gp120 JRFL protein in the expression and functionality of the alpha 7 nAChR’s in human monocytes derived macrophages. American Society for Biochemistry and Molecular Biology 17′ Annual Meeting, Chicago. April 22 – 26, 2017.


29. Cotto-Ríos S., Delgado-Velez M., Colón-Sáez J. O., Quesada-González O and Lasalde-Dominicci, J. A. HIV-1 gp120 IIIB/HIV-gp120 JRFL Mediated Human ?7 nAChR’s Up-regulation in macrophages and its Implications in the Cholinergic Anti-inflammatory Response (CAR). American Society Cell Biology, Philadelphia, PA. December 2-6, 2017.