Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit.

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Biaggi-Labiosa NM, Avilés-Pagán E, Caballero-Rivera D, Báez-Pagán CA, Lasalde-Dominicci JA. Neuropharmacology. 2015 Dec;99:273-84.