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University of Puerto Rico Molecular Sciences Research Center787-764-0000 ext 88125, 88126, 88127, 88128jlasalde@gmail.com
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NACHRS
Lasalde Laboratory – Universidad de Puerto Rico
NACHRS
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  • Home
  • PI Information
  • Projects
    • Ongoing Projects
    • Funding
  • Publications
  • Personnel
  • Resources
    • Equipment
    • Molecular Science Research Center
    • Puerto Rico
    • Outreach
  • Training
  • Presentations
    • Student Presentations 2017 – 2023
    • Student Presentations 2015 – 2016
    • Student Presentations 2014 – 2015
    • Student Presentations 2013 – 2014
  • Innovation
    • Intellectual Property
    • Commercialization
    • Significance

Projects

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Ongoing Projects

  • Innovation technology for membrane protein crystallization

  • Screening for Torpedo Acetylcholine receptor crystals from electric organ
    Structural studies on α7 neuronal nicotinic receptor

  • Cholesterol regulation of acetylcholine channel function

  • Acetylcholine receptor genes in the slow-channel syndrome

  • Mapping the lipid-protein interface of the Torpedo californica and muscle-type acetylcholine receptors

  • Molecular basis for neuronal nicotinic receptor upregulation: potential implications in HIV associated dementia (SNRP project)

  • Molecular Basis for the nicotine-induce upregulation of α4β2 neuronal receptors.

Innovation technology for membrane protein crystallization

Statin treatment results in a remarkable decline in locomotor activity in the αC418W transgenic mice

Recent Publications
Insights into Crystallization of Neuronal Nicotinic α4β2 Receptor in Polarized Lipid Matrices
January 28, 2025
Nicotinic Acetylcholine ceptor Expression in MerkelCell Carcinoma Is Associated With Clinical and Histopathologic Parameters
January 28, 2025
Identification of the native Torpedo californica nicotinic acetylcholine receptor’s glycan composition after a multi-step sequential purification method using MALDI-ToF MS. Proteomics
February 15, 2024
Contacts
University of Puerto Rico
Molecular Sciences Research Center


Structural and Molecular Biology Laboratory
Labs 111-114-115
PO Box 23360 San Juan, Puerto Rico
00931-3360

Laboratory:
787-764-0000
ext 88125, 88126, 88127, 88128
Fax: 787-753-3852
email: jlasalde@gmail.com

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