Dr. José A. Lasalde Dominicci is the Director of the Neuroimaging and Electrophysiology Facility and a Professor of Biology at the University of Puerto Rico, Río Piedras Campus. His research is focused on: (1) the structure function relationships of nicotinic receptors, (2), the role of lipid-protein interaction on acetylcholine receptor function, (3) the question of how genetically abnormal ion channels give rise to neurodegeneration, (4) studies towards a high-resolution structure of the Torpedo californica nAChR and a7-nAChRs, and more recently (5) the regulation of neuronal nicotinic receptor in HIV pathogenesis.

Education

  • Postdoc, Membrane Biology, University of California at Davis, Davis, CA
  • Postdoc, Biophysics, University of Puerto Rico, Institute of Neurobiology, San Juan, P.R.
  • PhD, Biochemistry, University of Puerto Rico, Río Piedras Campus, San Juan, P.R.
  • BS, Chemistry and Biology, University of Puerto Rico, Río Piedras Campus, San Juan, P.R.

Research Interests

  • Ion Channel Biophysics
  • Membrane Biology
  • Molecular Neuroscience
  • Neuromuscular Diseases
  • HIV-Associated Neurocognitive Disorders
  • Nicotinic Acetylcholine Receptor